Liquid chromatography in diagnosis of rare hemoglobin variant (Hb Chicago) and its combination with HB S: Hb Chicago/S trait and Hb Chicago/sickle cell disease
نویسندگان
چکیده
منابع مشابه
Hb in Diabetic Patients with Normal ( Hb A ) and Abnormal ( Hb S and Hb C ) Hemoglobins , as Measured
In a recent study (1 ) of diabetic patients with hemoglobins S and C (Hb S and Hb C), we showed a significant decrease in the proportion of glycosylated Hb, as measured by cation-exchange chromatography. We suggested ( I ) that these low values for glycosylated Hb might be caused by the inability of either Hb S or Hb C to undergo glycosylation or by their failure to be eluted from the column wi...
متن کاملRare hemoglobin variant Hb Yaizu observed in Turkey.
OBJECTIVE To determine the characteristic features of the rare hemoglobin (Hb) variant Hb Yaizu to enable laboratory diagnosis of the hemoglobin variants during screening programs. MATERIALS AND METHODS Genomic DNA was obtained from the 4 members of a family living in Denizli province, an Aegean region of Turkey. Blood cell counts, hemoglobin composition, hemoglobin electrophoresis (both alka...
متن کاملMeasurment of stable Glycosylated Hemoglobin (Hb A1) and Its unstable type (pre- Hb A1c) with the lon- exchange Chromatography in Diabetic patients
SUMMARY: At present, measurment of glycosylated hemoglobin, especially the stable fraction of hemoglobin (HbA1c) is one of the ways to control diabetes because this measurment can demonstrate total glycemia during last 1.2.3 months. Glycosylated hemoglobin is seen in 3 forms: Ala Alb A1c. Among these hemoglobin Alc is quantitively more than other 2 forms and its difference with other hemoglobi...
متن کاملPractical Attacks on HB and HB+ Protocols
HB and HB+ are a shared secret-key authentication protocols designed for low-cost devices such as RFID tags. HB+ was proposed by Juels and Weis at Crypto 2005. The security of the protocols relies on the learning parity with noise (LPN) problem, which was proven to be NP-hard. The best known attack on LPN by Levieil and Fouque [13] requires subexponential number of samples and sub-exponential n...
متن کاملMolecular and haematological characterization of compound Hb E/Hb Pyrgos and Hb E/Hb J-Bangkok in Thai patients.
We describe haematological and DNA characterization of haemoglobinopathies in Thai adolescents caused by compound heterozygosities for Hb E [beta26(B8) Glu-Lys] and two other beta-globin chain variants, Hb Pyrgos [beta83(EF7) Gly-Asp] and Hb J Bangkok [beta56(D7) Gly-Asp]. Hb analysis demonstrated that although these two beta-chain variants have separated elution profiles on liquid chromatograp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1996
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/42.5.774